CBMP Graduate Student Publications
2021
Bagalkot TR, Block ER, Bucchin K, Balcita-Pedicino JJ, Calderon M, Sesack SR, Sorkin A. Dopamine Transporter Localization in Medical Forebrain Bundle Axons Indicates Its Long-Range Transport Primarily by Membrane Diffusion with a Limited Contribution of Vesicular Traffic on Retromer-Positive Compartments. Neurosci. 2021 Jan 13;41(2):234-250. Doi: 10.1523/JNEUROSCI.0744-20.2020. Epub 2020 Nov 24. PMID: 33234607 Free PMC article.
2020
Rudich P, Snoznik C, Puleo N, Lamitina T. Measuring RAN Peptide Toxicit in C. Elegans. J Vis Exp. 2020 Apr 30;(158):10.3791/61024. Doi: 10.3791/61024. PMID: 32420986 Free PMC article.
Rudich P, Watkins S, Lamitina T. PolyQ-Independent Toxicity Associated with Novel Translational Products from CAG Repeat Expansions. PLoS One, 2020 Apr 2;15(4):e0227464. Doi: 10.1371/journal.pone. 022764. eCollection 2020 PMID: 32240172 Free PMC article.
Li T, Zhang Z, Bartolacci JG, Dwyer GK, Liu Q, Mathews LR, Velayutham M, Roessing AS, Lee UP, Dai H. Shava S, Oberbarnscheidt MH, Dziki JL, Mullet SJ, Wendell SG, Wilkinson JD, Webber SA, Wood-Trageser M, Watkins SC, Demetris AJ, Hussey GS, Badylak SF, Turnquist HR. Graft IL-33 Regulates Infiltrating Macrophages to Protect Against Chronic Rejection. J Clin Vest. 2020 Oct 1;130(10):5397-5412. Doi: 10.1172/JCI133008. PMID: 32644975 Free PMC article.
2019
Eaton AF, Clayton DR, Ruiz WG, Griffiths SE, Rubio ME, Apodaca G. Expansion and contraction of the Umbrella Cell Apical Junctional Ring in Response to Bladder Filling and Voiding. Mol Biol. Cell, 2019 Jun 5:mbcE19020115. Doi: 10.1091/mbc.E19-02-0115. [Epub ahead of print] PMID: 31166831
Li Y, Merkel CD, Zeng X, Heier JA, Cantrell PS, Sun M, Stolz DB, Watkins SC, Yates, NA, Kwiatkowski AV. The N-Cadherin Interactome in Primary Cardiomyocytes as Defined Using Quantitative Proximity Proteomics. J Cell Sci. 2019 Feb 1;132(3). Pii: jcs221606. Doi: 10.1242/jcs.221606. PMID: 30630894
Kullmann AF, Truschel ST, Wolf-Johnston AS, McDonnell BM, Lynn AM, Kanai AJ, Kessler TM, Apodaca G, Birder LA. Acute Spinal Cord Injury is Associated with Mitochondrial Dysfunction in Mouse Urothelium. Neurourol Urodyn. 2019 Aug;38(6):1551-1559. Doi: 10.1002/nau.24037. Epub 2019 May 18. PMID: 31102563
Bulterys MA, Wagner B, Redard-Jacot M, Suresh A, Pollock NR, Moreau E, Denkinger CM, Drain PK, Broger T. Point-Of-Care Urine LAM Tests for Tuberculosis Diagnosis: A Status Update. J Clin Med. 2019 Dec 31;9(1). Pii: E111. Doi: 10.3390/jcm9010111. Review. PMID: 31906163
Yatsenko SA, Wood-Trageser M, Chu T, Jiang H, Rajkovic A. A High-Resolution X Chromosome Copy-Number Variation Map in Fertile Females and Women with Primary Ovarian Insufficiency. Genet. Med. 2019 Oct;21(10):22075-2284. Doi: 10.1038/s41436-019-05052. Epub 2019 Apr 5. PMID: 30948856
Guerriero CJ, Gomez YK, Daskivich GJ, Reutter KR, Augustine AA, Weiberth KF, Nakatsukasa K, Grabe M, Brodsky JL. Harmonizing Experimental Data with Modeling to Predict Membrane Protein Insertion in Yeast. Biophys J. 2019 Aug 20;117(4):668—678. Doi: 10.1016j.bpj.2019.07.013. Epub 2019 Jul 16. PMID: 31399214
Doonan LM, Guerriero CJ, Preston GM, Buck TM, Khazanov N, Fisher EA, Senderowitz H, Brodsky JL. Hsp 104 Facilitates the Endoplasmic-Reticulum-Associated Degradation of Disease-Associated and Aggregation-Prone Substrates. Protein Sci. 2019 Jul;28(7):1290-1306. Doi: 10.1002/pro.3636. Epub 2019 May 20 PMID: 31050848
Needham PG, Guerriero CJ, Brodsky JL. Chaperoning Endoplasmic Reticulum-Associated Degradation (ERAD) and Protein Conformational Diseases. Cold Spring Harb Perspect Biol. 2019 Aug 1;11(8). Pii: a033928. Doi: 10.1101/cshperspect.a033928. Review. PMID: 20670468
2018
Wills RC, Goulden BD, Hammond GRV. Genetically Encoded Lipid Biosensors. Mol Biol Cell. 2018 Jul 1;29(13):1526-1532. Doi: 10.1091/mbc.E17-12-0738. PMID: 29953345
Sohn M, Korzeniowski M, Zewe JP, Wills RC, Hammond GRV, Humpolickova J, Vrzal L, Chalupska D, Veverka V, Fairn GD, Boura E, Balla T. PI(4.5) P2 Controls Plasma Membrane PI4P and PS Levels Via ORP5/8 Recruitment to ER-PM Contact Sites. J Cell Biol. 2018 May 7;217(5):1797-1813. Doi: 10.1083/jcb.201710095. Epub 2018 Feb 22. PMID: 29472386
Zewe JP, Wills RC, Sangappa S, Goulden BD, Hammond GR. SAC1 Degrades its Lipid Substrate PtdIns4P in the Endoplasmic Reticulum to Maintain a Steep Chemical Gradient with Donor Membranes. Elife. 2018 Feb 20;7. Pii: e35588. Doi: 10.7554/eLife.35588. PMID: 29461204
Rudich P, Lamitina T. Models and Mechanisms of Repeat Expansion Disorders: A Worm’s Eye View. J Genet. 2018 Jul;97(3):665-677. PMID: 30027902
Truschel ST, Clayton DR, Bechel JM, Yabes JG, Yao Y, Wolf-Johnston A, Birder LA, Apodaca G. Age-Related Endolysosome Dysfuction in the Rat Urothelium. PLoS, One. 2018 Jun 8;13(6):e0198817. Doi: 10.1371/journal.pone.0198817. eCollection 2018. PMID: 29883476
Kaya C, Cheng MH, Block ER, Bartol TM, Sejnowski TJ, Sorkin A, Faeder JR, Bahar I. Heterogeneities in Axonal Structure and Transporter Distribution Lower Dopamine Reuptake Efficiency. eNeuro. 2018 Feb 5;5(1). Pii: ENEURO.0298-17.2017. doi: 10.1523/EMEIRP.0298-17.2017 eCollection 2018 Jan-Feb. PMID: 29430519
Ren Y, Diao F, Katari S, Yatsenko S, Jiang H, Wood-Trageser MA, Rajkovic A. Functional Study of a Novel Missense Single-Nucleotide Variant of NUP107 in Two Daughters of Mexican Origin with Premature Ovarian Insufficiency. Mol Genet Genomic med. 2018 Mar;6(2):276-281. Doi: 10.1002/mgg3.345. Epub 2018 Jan 24. PMID: 29363275
Preston GM, Guerriero CJ, Metzger MB, Michelis S, Brodsky JL. Substrate Insolubility Dictates Hsp 104-Dependent Endoplasmic-Reticulum-Associated Degradation. Mol Cell. 2018 Apr 19;70(2):242-253.e6. doi: 10.1016/j.molcel.2018.03.016. PMID: 29677492
Gurbuz F, Desai S, Diao F, Turkkahraman D, Wranitz F, Wood-Trageser M, Shin YH, Kotan LD, Jiang H, Witchel S, Gurtunca N, Yatsenko S, Mysiliwec D, Topaloglu K, Rajkovic A. Novel Inactivating Mutations of the DCAF17 Gene in American and Turkish Families Cause Male Infertility and Female Subfertility in the Mouse Model. Clin Genet. 2018 Apr;93(4):853-859. Doi: 10.1111/cge. 13183. Epub 2018 Jan 24. PMID: 29178422
Delorme-Axford E, Abernathy E, Lennemann NJ, Bernard A, Ariosa A, Coyne CB, Kirkegaard K, Klionsky DJ The Exoribonuclease Xrn1 Is a Post-Transcriptional Negative Regulator of Autophagy. Autophagy. 2018 Feb 21:1-47. Doi: 10.1080/15548627.2018.1441648 [Epub ahead of print] PMID: 29465287
Zarakowska E, Czerwinska J, Tupalska A, Yousefzadeh MJ, Gregg SQ, St Croix CM, Niedernhofer LJ, Foksinski M, Gackowski D, Szpila A, Starczak M, Tudek B, Olinski R Oxidation Products of 5-Methyl Cytosine are Decreased in Senescent Cells and Tissues of Progeroid Mice. J Gerontol A Biol Sci Med Sci. 2018 Feb 3. Doi: 10.1093/Gerona/gly012. [Epub ahead of print] PMID: 29415265
2017
Willett R, Martina JA, Jewe JP, Wills R, Hammond GRV, Puertollano R. TFEB Regulates Lysosomal Positioning by Modulating TMEM55B Expression and JIP4 Recruitment to Lysosomes. Nat Commun. 2017 Nov 17;8(1):1580. Doi: 10.1038/s41467-017-01871-z. PMID: 29146937
Heier JA, Dickinson DJ, Kwiatkowski AV. Measuring Protein Binding to F-actin by Co-Sedimentation. J Vis Exp. 2017 May 18;(123). Doi: 10.3791/55613. PMID: 28570520
Kang H, Bang I, Jin KS, Lee B, Lee J, Shao X, Heier JA, Kwiatkowski AV, Nelson WJ, Hardin J, Weis WI, Choi HJ. Structural and Functional Characterization of Caenorhabditis elegans α-catenin Reveals Constitutive Binding to β-catenin and F-actin. J Biol Chem. 2017 Apr 28;292(17):7077-7086. Doi: 10.1074/jbc.M116.769778. Epub 2017 Mar 15. PMID: 28298447
Rudich P, Snoznik C, Watkins SC, Monaghan J, Pandey UB, Lamitina ST. Nuclear Localized C9orf72-Associated Arginine-Containing Dipeptides Exhibit Age-Dependent Toxicity in C. Elegans. Hum Mol Genet. 2017 Dec 15;26(24):4916-4928. Doi: 10.1093/hmg/ddx372. PMID: 29036691
Trac PT, Thai TL, Linck V, Zou L, Greenlee M, Yue Q, Al-Khalili O, Alli AA, Eaton AF, Eaton DC Alveolar Nonselective Channels are ASIC1a/α-ENaC Channels and Contribute to AFS. Am J Physiol Lung Cell Mol Physiol. 2017 Jun 1;312(6):L797-L811. Doi: 10.1152/ajplung.00379.2016. Epub 2017 Mar 10. PMID: 28283476 PMCID: PMC5495939
Guerriero CJ, Reutter KR, Augustine AA, Preston GM, Weiberth KF, Mackie TD, Cleveland-Rubeor HC, Bethel NP, Callenberg KM, Nakatsukasa K, Grabe M. Brodsky JL Ransmembrane Helix Hydrophobicity is an Eenergetic Barrier during the Rretrotranslocation of Integral Membrane ERAD Substrates. Mol Biol Cell. 2017 Jul 15;28(15);2076-2090. Doi: 10.1091/mbc.E17-03-084. Epub 2017 May 24. PMID: 28539401
Preston, GM, Brodsky JL The Evolving Role of Ubiquitin Modification in Endoplasmic Reticulum-Associated Degradation. Biochem J. 2017 Feb 15;474(4):445-469. Doi: 10.1042/CBJ20160582. Review. PMID: 28159894
Buck TM, Jordahl AS, Yates ME, Preston, GM, Cook E, Kleyman TR, Brodsky JL. Interactions Between Intersubunit Transmembrane Domains Regulate the Chaperone-Dependent Degradation of an Oligomeric Membrane Protein. Biochem J. 2017 Feb 1;474(3):357-376. Doi: 10.1042/BCJ20160760. Epub 2016 Nov 30. PMID: 27903760
Klemens CA, Edinger RS, Kightlinger L, Liu X, Butterworth MB. Nkyrin G Expression Regulates Apical Delivery of the Epithelial Sodium Cannel (ENaC). J Biol Chem. 2017 Jan 6;292(1):375-385. Doi: 10.1074/jbc.M116.753616. Epub 2016 Nov 28. PMID: 27895120
Liu, X, Edinger RS, Klemens CA, Phua YL, Bodnar AJ, LaFramboise WA, Ho J, Butterworth MB A MicroRNA Cluser miR-23-24-27 Is Upregulated by Aldosterone in the Distal Kidney Nepron Where It Alters Sodium Transport. J Cell Physiol. 2017 Jun;232(6):1306-1217. Doi: 10.1022/jcp.25599. Epub 2017 Jan 5. PMID: 27636893
Preston GM. Profiling the Extended Phenotype of Plant Pathogens: Challenges in Bacterial Molecular Plant Pathology. Mol Plant Pathol. 2017 Apr;18(3):443-456. Doi: 10.1111/mpp.12530. Epub 2017 Feb 16. Review. PMID: 28026146
Liu X, Edinger RS, Klemens CA, Phua YL, Bodnar AJ, LaFramboise WA, Ho J, Butterworth MB. A MicroRNA Cluster miR-23-24-27 is Upregulated by Aldosterone in the Distal Kidney Nephron Where it Alters Sodium Transport. J Cell Physiol. 2017 Jun;232(6):1306-1317. Doi: 10.1002/jcp.25599. Epub 2017 Jan 5 PMID: 27636893
Yatsenko SA, Mittal P, Wood-Trageser MA, Jones NW, Surti U, Edwards RP, Sood AK, Rajkovic A. Highly Heterogeneous Genomic Landscape of Uterine Leiomyomas by Whole Exome Sequencing and Genome-Wide Arrays. Fertil Steril. 2017 Feb;107(2):457-466 e9. Doi: 10.1016/j.fertnstert.2016.10.035. Epub 2016 Nov 23. PMID: 27889101
Desai S, Wood-Trageser M, Matic J, Chipkin J, Jiang H, Bachelot A, Dulon J, Sala C, Barbieri C, Cocca M, Toniolo D, Touraine P, Witchel S, Rajkovic A. MCM8 and MCM9 Nucleotide Variants in Women with Primary Ovarian Insufficiency. J Clin Endocrinol Metab. 2017 Feb 1;102(2):576-582. Doi: 10.1210/jc.2016-2565. PMID: 27802094
2016
Wickline ED, Dale IW, Merkel CD, Heier JA, Stolz DB, Kwiatkowski, AV. Α-T-Catenin Is a Constitutive Actin-Binding α-Catenin That Directly Couples the Cadherin˖Catenin Complex to Actin Filaments. J Biol Chem. 2016 Jul 22;291(30): 15687-99. Doi: 10.1074/jbc.M116.735423. Epub 2016 May 26. PMID: 27231342
Liu X, Edinger RS, Klemens CA, Phua YL, Bodnar AJ, LaFramboise WA, Ho J, Butterworth MB. A MicroRNA Cluster miR-23∼24∼27 Is Upregulated by Aldosterone in the Distal Kidney Nephron where it Alters Sodium Transport. J Cell Physiol. 2016 Sep 16. Doi: 10.1002/jcp.25599. [Epub ahead of print] PMID: 27636893
Ma L, Umasankar PK, Wrobel AG, Lymar A, McCoy AJ, Holkar SS, Jha A, Pradhan-Sundd T, Watkins SC, Owen DJ, Traub LM. Transcient Fcho1/2˖Eps15/R˖AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding. Dev Cell. 2016 Jun 6;37(5):428-43. Doi: 10.1 016/j.devcel.2016.05.003. Epub 2016 May 26.PMID: 27237791 Free PMC Article
Sabnis AJ, Guerriero CJ, Olivas V, Sayana A, Shue J, Flanagan J, Asthana S, Paton AW, Paton JC, Gestwicki JE, Walter P, Weissman JS, Wipf P, Brodsky JL, Bivona TG. Combined Chemical-Genetic Approach Identifies Cytosolic HSP70 Dependence in Rhabdomyosarcoma. Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):9015-20. Doi: 10.1073/pnas. 1603883113. Epub 2016 Jul 22. PMID: 27450084
Shi S, Luke CJ, Miedel MT, Silverman GA, Kleyman TR. Activation of the Caenorhabditis Elegans Degenerin Channel by Shear Stress Requires the MEC-10 Subunit. J Biol Chem. 2016 July 1;291(27):14012-22. Doi: 10.1074/jbc.M116.718031. Epub 2016 May 4. PMID: 27189943
McConkey CA, Delorme-Axford E, Nickerson CA, Kim KS, Sadovsky Y, Boyle JP, Coyne CB. Ree-dimensional Culture System Recapitulates Placental Syncytiotrophoblast Development and Microbial Resistance. Sci Adv. 2016 Mar 4;2(3):e1501462. Doi: 10.1126/sciadv.1501462. eCollection 2016 Mar. PMID: 26973875 Free PMC Article
Yatsenko SA, Bakos HA, Vitullo K, Kedrov M, Kishore A, Jennings BJ, Surti U, Wood-Trageser MA, Cercone S, Yatsenko AN, Rajkovic A, Iannaccone A. Olution Microarray Analysis Unravels Complex Xq28 Aberrations in Patients and Carriers Affected by X-Linked Blue Cone Monochromacy. Clin Genet. 2016 Jan;89(1):82-7. Doi: 10.1111/cge. 12638. Epub 2015 Jul 28. PMID: 26153062 Free PMC Article
2015
Montalbetti N, Rued AC, Clayton DR, Ruiz WG, Bastacky SI, Prakasam HS, Eaton AF, Kullmann FA, Apodaca G, Carattino MDo. Increased Urothelial Paracellular Transport Promotes Cystitis. Am J Physiol Renal Physiol. 2015 Dec 15;309(12):F1070-81. Doi: 10.1152/ajprenal.00200.2015/ Epub 2015 Sep 30. PMID: 26423859
Yu L, Eaton AF, Yue Q, Bao HF, Ma HP, Cuppoletti J, Eaton DC Unoprostone Activation of BK (KCa1.1) Channel Splice Variants. Biochim Biophys Acta. 2015 Nov;1848(11 PtA):2859-67. Doi: 10.1016/j.bbamen.2015.08.005. Epub 2015 Aug 13. PMID: 26277265 PMCID: PMC4598293
Cummings EE, O’Reilly LP, King DE, Silverman RM, Miedel MT, Luke CJ, Perlmutter DH, Silverman GA, Pak SC. Deficient and Null Variants of SERPINA1 Are Proteotoxic in a Caenorhabditis Elegans Model of α1-Antitrypsin Deficiency. PLoS One. 2015 Oct 29;10(10):e0141542. Doi: 10.1371/journal.pone.0141542 eCollection 2015. PMID: 26512890
Niehaus JZ, Miedel MT, Good M. Wyatt AN, Pak SC, Silverman GA, Luke CJ. SERPINB12 is a Slow-Binding Inhabitor of Granzyme A and Hepsin. Biochemistry. 2015 Nov 17;54(45):6756-9. Doi: 10.1021/acs.biochem.5b01042. Epub 2015 Nov 5. PMID: 26497600
Cheng MH, Block E, Hu F, Cobanoglu MC, Sorkin A, Bahar I. Insights into the Modulation of Dopamine Transporter Function by Amphetamine, Orphenadrine, and Cocaine Binding. Front Neurol. 2015 Jun 9;6:134. Doi: 10.3389/fneur.2015.001134. eCollection 2015. PMID: 26106364 Free PMC Article
Katari S, Wood-Trageser MA, Jiang H, Kalynchuk E, Muzumdar R, Yatsenko SA, Rajkovic A. Novel Inactivating Mutation of the FSH Receptor in Two Siblings of Indian Origin with Premature Ovarian Failure. J Clin Endocrinol Metab. 2015 Jun;100(6):2154-7. Doi: 10.110/jc.2015-1401. Epub 2015 Apr 15. PMID: 25875778
AlAsiri S, Basit S, Wood-Trageser MA, Yatsenko SA, Jeffries EP, Surti U, Ketterer DM, Afzal S, Ramzan K, Faiyaz-Ul Haque M, Jiang H, Trakselis MA, Rajkovic A. Exome Sequencing Reveals MCM8 Mutation Underlies Ovarian Failure and Chromosomal Instability. J Clin Invest. 2015 Jan;125(1):258-62. Doi: 10.1172/JC178473. Epub 2014 Dec 1. PMID: 25437880
Marcoline FV, Bethel N, Guerriero CJ, Brodsky JL, Grabe M. Membrane Protein Properties Revealed through Data-Rich Electrostatics Calculations. Structure. 2015 Aug 4;23(8):1526-37. Doi: 10.1016/j.str.2015.05.014. Epub 2015 Jun 25. PMID: 26118532
Cheng MH, Block E, Hu F, Cobanoglu MC, Sorkin A, Bahar I. Insights into the Modulation of Dopamine Transporter Function by Amphetamine, Orphenadrine, and Cocaine Binding. Front Neurol. 2015 Jun 9;6:134. Doi: 10.3389/fneur.2015.00134. eCollection 2015. PMID: 26106364
Silverman RM, Cummings EE, O'Reilly LP, Miedel MT, Silverman GA, Luke CJ, Perlmutter DH, Pak SC. Eaggregation-prone intracellular serpin SRP-2 fails to transmit the ER in Caenorhabditis elegans. Genetics. 2015 May;200(10:207-19. Doi: 10.1534/genetics. 115.176180. Epub 2015 Mar 18. PMID: 25786854
Block ER, Nuttle J, Balcita-Pedicino JJ, Caltagarone J, Watkins SC, Sesack SR, Sorkin A. Brain Region-Specific Trafficking of the Dopamine Transporter. JNeurosci. 2015 Sep 16;35(37):12845-58. Doi: 10.1523/JNEUROSCI. 1391-15.2015. PMID: 26377471
Reay DP, Bastacky SI, Wack KE, Stolz DB, Robbins PD, Clemens PR. D-Amino Acid Substitution of Peptide-Mediated NF-κB Suppression in mdx Mice Preserves Therapeutic Benefit in Skeletal Muscle, but Causes Kidney Toxicity. Mol Med. 2015 May 22;21:442-52. Doi: 10.2119/molmed.2013.00141. PMID: 26018805 Free PMC Article
2014
Wood-Trageser MA, Gurbuz F, Yatsenko SA, Jeffries EP, Kotan LD, Surti U, Ketterer DM, Matric J, Chipkin J, Jing H, Trakselis MA, Topaloglu AK, Rajkovic A. MCM9 Mutations are Associated with Ovarian Failure, Short Stature, and Chromosomal Instability. Am J Hum Genet. 2014 Dec 4;95(6):754-62. DOI: 10.1016/j.ajhg.2014. 11.002. PMID: 25480036
Szalinski CM, Labilloy A, Bruns JR, Weisz OA. VAMP7 Modulates Ciliary Biogenesis in Kidney Cells. PLoS One. 2014 Jan22;9(1):e86425. Doi: 10.1371/journal.pone.0086425. eCollection 2014. PMID: 24466086 Free PMC Article
Kolb AR, Needham PG, Rothenberg C, Guerriero CJ, Welling PA, Brodsky JL. ESCRT regulates surface expression of the Kir2.1 potassium channel. Mol Biol Cell. 2014 Jan;25(2):276-89. Doi: 10.1091/mbc.E13-07-0394. Epub 2013 Nov 13. PMID: 24227888
Saunders MJ, Block E, Sorkin A, Waggoner AS, Bruchez MP. A bifunctional converter: fluorescein quenching scFv/fluorogen activating protein for photostability and improved signal to noise in fluorescence experiments. Bioconjug Chem. 2014 Aug 20;25(8):1556-64. Doi: 10.1021/bc500273n. Epub 2014 Aug 6. PMID: 25072845
Kolb AR, Needham PG, Rothenbert C, Guerriero CJ, Welling PA, Brodsky JL. ESCRT regulates surface expression of the Kir2.1 potassium channel. Mol Biol Cell. 2014 Jan;25(2):276-89. Doi: 10.1091/mbc.E13-07-0394. Epub 2013 Nov 13. PMID: 24227888
Long OS, Benson JA, Kwak JH, Luke CJ, Gosai SJ, O'Reilly LP, Wang Y, LiJ, Vetica AC, Miedel MT, Stolz DB, Watkins SC, Züchner S, Perlmutter DH, Silverman GA, Pak SC. A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover. Hum Mol Genet. 2014 Oct 1;23(19):5109-22. Doi: 10.1093/hmg/ddu235. Epub 2014 May 16. PMID: 24838286
O'Reilly LP, Long OS, Cobanoglu MC, Benson JA, Luke CJ, Miedel MT, Hale P. Perlmutter DH, Bahar I, Silverman GA, Pak SC. A genome-wide RNAi screen identifies potential drug targets in a C. elegans model of α1-antitrypsin deficiency. Hum Mol Genet. 2014 Oct 1;23(19):5123.32. doi: 10.1093/hmg/ddu236. Epub 2014 may 16. PMID: 24838285
Miedel MT, Zeng X, Yates NA, Silverman GA, Luke CJ. Isolation of serpin-interacting proteins in C. elegans using protein affinity purification. Methods. 2014 Aug 1;68(30:536-41. Doi: 10.1016/j.ymeth.2014.04.019. Epub 2014 May 2. PMID: 24798811
Chakraborty S, Umasankar PK, Preston GM, Khandelwal P, Apodaca G, Watkins SC, Traub LM. A phosphotyrosine switch for cargo sequestration at clathrin-coated buds. J Biol Chem. 2014 Jun 20;289(25):17497-514. doi: 10.1074/jbc.M114.556589. Epub 2014 May 5. PMID:24798335[PubMed - indexed for MEDLINE] PMID:24798335[PubMed - indexed for MEDLINE] PMCID:PMC4067187[Available on 2015-06-20]
Bayer A, Delorme-Axford E, Sleigher C, Frey TK, Trobaugh DW, Klimstra WB, Emert-Sedlak LA, Smithgall TE, Kinchington PR, Vadia S, Seveau S, Boyle JP, Coyne CB, Sadovsky Y. Human trophoblasts confer resistane to viruses implicated in perinatal infection. Am J Obstet Gynecol. 2014 Aug 6. pii: S0002-9378(14)00809-6. doi: 10.1016/j.ajog.2014.07.060. [Epub ahead of print] PMID:25108145
Delorme-Axford E, Morosky S, Bomberger J, Stolz DB, Jackson WT, Coyne CB.
BPIFB3 regulates autophagy and coxsackievirus B replication through a noncanonical pathway independent of the core initiation machinery. MBio. 2014 Dec 9;5(6):e02147. doi: 10.1128/mBio.02147-14.PMID:25491355[PubMed - in process] Free PMC Article
Chakraborty S, Umasankar PK, Preston GM, Khandelwal P, Apodaca G, Watkins SC, Traub LM.A Phosphotyrosine switch for cargo sequestration at clathrin coated buds. J Biol Chem. 2014 Jun 20;289(25):17497-514. doi: 10.1074/jbc.M114.556589. Epub 2014 May 5. PMID:24798335{PubMed – indexed for MEDLINE} Szalinski CM, Labilloy A, Bruns JR, Weisz OA. VAMP modulates ciliary biogenesis in Kidney cells PLoS One. 2014 Jan 22;9(1):e86425. doi: 10.1371/journal.pone.0086425. eCollection 2014. PMID:24466086Free PMC Article
Umasankar PK, Ma L, Thieman JR, Jha A, Doray B, Watkins SC, Traub LM. A clathrin coat assembly role for the muniscin protein central linker revealed by TALEN-mediated gene editing. Elife. 2014 Oct 10;3. doi: 10.7554/eLife.04137.PMID:25303365[PubMed - in process] Free PMC Article
Solomon JD, Heitzer MD, Liu TT, Beumer JH, Parise RA, Normolle DP, Leach DA, Buchanan G, DeFranco DB. VDR activity is differentially affected by Hic-5 in prostate cancer and stromal cells. Mol Cancer Res. 2014 Aug;12(8):1166-80. doi: 10.1158/1541-7786.MCR-13-0395. Epub 2014 May 13.PMID:24825850[PubMed - in process]
Umasankar PK, Ma L, Thieman JR, Jha A, Doray B, Watkins SC, A clathrin coat assembly role for the muniscin protein central linker revealed by TALEN-mediated gene editing.
Elife. 2014 Oct 10;3. doi: 10.7554/eLife.04137.PMID:25303365[PubMed - in process] Free PMC Article
Jha A, Traub LM. Visualization of clathrin-mediated endocytosis in live Drosophila egg chambers. Methods Mol Biol. 2014;1174:349-60. doi: 10.1007/978-1-4939-0944-5_24.PMID:24947394[PubMed - indexed for MEDLINE] Free PMC Article
2013
Neal MD, Jia H, Eyer B, Good M, Guerriero CJ, Sodhi CP, Afrazi A, Prindle T Jr, Ma C, Branca M, Ozolek J, Brodsky JL, Wipf P, Hackam DJ. Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors. PLoS One. 2013 Jun 12;8(6):e65779. Doi: 10.1371/journal.pone.0065779. Prin 2013. PMID: 23776545
Guerriero CJ, Weiberth KF, Brodsky JL. Hsp70 targets a cytoplasmic quality control substrate to the San1p ubiquitin ligase. JBoil Chem. 2013 Jun 21;288(25):18506-20. Doi: 10.1074/fbc.M113.475905. Epub 2013 May 7. PMID: 23653356
Szalinski CM, Guerriero CJ, Ruiz WG, Docter BE, Rbaibi Y, Pastor-Soler NM, Apodaca G, Puthenveedu MA, Weisz OA. PIP5KIβ selectively modulates apical endocytosis in polarized renal epithelial cells. PLoS One. 2013;8(1):e53790. Doi: 10.1371/journal.pone.0053790. Epub 2013 Jan 16. PMID: 23342003
Neal MD, Jia H, Eyer B, Good M. Guerriero CJ, Sodhi CP, Afrazi A, Prindle T Jr, Ma C, Branca M, Ozolek J, Brodsky JL, Wipf P, Hackam DJ. Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors. PLoS One. 2013 Jun 12;8(6):e65779. Doi: 10.1371/journal.pone.0065779. Print 2013.PMID: 23776545
Guerriero CJ, Weiberth KF, Brodsky JL. Hsp70 targets a cytoplsmic quality control substrate to the San1p ubiquitin ligase. J Biol Chem. 2013 Jun 21;288(25):18506-20. Doi: 10.1074/jbc.M113.475905. Epub 2013 May 7. PMID: 23653356
Kilpatrick K, Novoa JA, Hancock T, Guerriero CJ, Wipf P. Brodsky JL, Segatori L. Chemical induction of Hsp70 reduced α-synuclein aggregation in neuroglioma cells. ACS Chem Biol.2013 Jul 19;8(7):146008. Doi: 10.1021/cb400017h. Epub 2013 May 1. PMID: 23594135
Heid ME, Keyel PA, Kamga C, Shiva S, Watkins SC, Salter RD. Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation. J Immunol.2013 Nov 15;191(10):5230-8. Doi: 10.4049/jimmunol. Epub Oct 2. PMID: 24089192
Weixel KM, Marciszyn A, Alzamora R. Li H, Fischer O, Edinger RS, Hallows KR, Johnson JP. Resveratrol inhibits the epithelial sodium channel via phopshoinositides and AMP-activated protein kinase in kidney collecting duct cells. PLoS One. 2013 Oct 24;8(10):e78019 doi: 10.1371/journal.pone.0078019. eCollection 2013. PMID:24205069
Suresh A, Subedi K, Kyathanahalli C, Jeyasuria P, Condon JC. Uterine endoplasmic reticulum stress and its unfolded protein response may regulate caspase 3 activation in the pregnant mouse uterus. PLoS One. 2013 Sep 13;8(9):e75152. doi: 10.1371/journal.pone.0075152. eCollection 2013. PMID:24058658Free PMC Article
Chotoo CK, Silverman GA, Devor DC, Luke CJ. A small conductance calcium-activated K+ channel in C. Elegans, KCNL-2, plays a role in the regulation of the rate of egg-laying PLoS One, 2013 Sep 10;8(9):e75869. Doi: 10.1371/journal.pone.0075869. PMID: 24040423
Roh DS, Du Y, Gabriele ML, Robinson AR, Niedernohofer LJ, Funderburgh JL. Age-related dystrophic changes in corneal endothelium from DNA repair-deficient mice. Aging Cell. 2013 Dec; 12(6):1122-31. Doi: 10.1111/acel. 12143. Epub 2013 Sep 1. PMID: 2397039
Delorme-Axford E, Bayer A, Sadovsky Y, Coyne CB Autophagy as a mechanism of antiviral defense at the maternal-fetal interface. Autophagy. 2013 Dec 1;9(12):2173-2174. Epub 2013 Oct 8. Review. PMID: 24231730
Delorme-Axford E, Doner RB, Mouillet JF, Chu T, Bayer A, Ouyang Y, Wang T, Soltz DB, Sarka SN, Morelli AE, Sadovsky Y, Coyne CB. Human placental trophoblasts confer viral resistance to recipient cells. Proc Natl Acad SCI U S A. 2013 July 16;110(29): 12048-53. Doi: 10.1073/pnas. 1304718110. Epub 2013 Jul 1. PMID: 23818581
Delorme-Axford E, Sadovsky Y, Coyne CB. Lipid-raft-and Src family kinase-dependent entry of Coxsackievirus B (CVB) into human placental trophoblasts. J Virol. 2013 May 29. In press. PMID: 23720726
Lee SE, Mehra R, Fujita M, Roh DS, Long C, Lee W. Funderburgh JL, Ayares DL, Copper DK, Hara H. Characterization of Porcine Corneal Endothelium for Xenotransplantation. Semin Ophthalmol. 2013 June 12. [Epub ahead of print] PMID: 23758340
Szalinski CM, Guerriero CJ, Ruiz WG, Docter BE, Rbaibi Y, Pastor-Soler NM, Apodaca G, Puthenveedu MA, Weisz OA. PIP5KIβ selectively modulates apical endocytosis in polarized renal epithelial cells. PLoS One. 2013;8(1):e53790. doi: 10.1371/journal.pone.0053790. Epub 2013 Jan 16.PMID:23342003[PubMed - indexed for MEDLINE] Free PMC Article
Lee SE, Mehra R, Fujita M, Roh DS, Long C, Lee W, Funderburgh JL, Ayares DL, Cooper DK, Hara H. Characterization of Porcine Corneal Endothelium for Xenotransplantation. Semin Ophthalmol. 2013 Jun 12. [Epub ahead of print] PMID: 23758340
2012
Guerriero CJ, Brodsky JL. The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology. Physiol Rev. 2012 Apr;92(2):537-76. Doi: 10.1152/physrev.00027.2011. Review. PMID: 22535891
Butterworth MB, Edinger RS, Silvis MR, Gallo Ll, Liang X, Apodaca G, Frizzell RA, Johnson JP. Rab11b regulates the trafficking and recycling of the epithelial sodium channel (ENaC). Am J Physiol Renal Physiol. 2012 Mar 1;302(5):F581.90. 10.1152/ajprenal.00304.2011. Epub 2011 Nov 30. Erratum in: Am J Physiol Renal Physiol. 2012 Jul;303(1):F163. Frizzell, Raymond A. PMID: 22129970
Guerriero CJ, Brodsky JL. The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology. Physiol Rev. 2012 Apr;92(2):537-76. Doi: 10.1152/physrev.00027.2011. Review PMID: 22535891
Miedel MT, Graf NJ, Stephen KE, Long OS, Pak SC, Perlmutter DH, Silverman GA, Luke CJ. A pro-cathepsin L mutant is a luminal substrate for endoplasmic-reticulum-associated degradation in C. elegans. PLoS One. 2012;7(7):e40145. Doi: 10.1371/journal.pone.0040145. Epub 2012 Jul 2. PMID: 22768338
Colletti GA, Miedel MT, Quinn J, Andharia N, Weisz OA, Kiselyov K. Loss of lysosomal ion channel transient receptor potential channel mucolipin-1 (TRPML1) leads to cathepsin B-dependent apoptosis. J Biol Chem. 2012 Mar 9;287(11):8082-91. Doi: 10.1074/jbc.M111.285536. Epub 2012 Jan 18 PMID: 22262857
Keyel PA, Heid ME, Watkins SC, Salter RD. Visualization of bacterial toxin induced responses using live cell fluorescence microscopy. J Vis Exp. 2012 Oct 1;(68):e4227 Doi: 10.3791/4227. PMID: 23052609
Bozym RA, Delorme-Axford E, Harris K, Morosky S, Ikizler M, Dermody TS, Sarkar SN, Coyne CB. Focal adhesion kinase is a component of antiviral RIG-I-like receptor signaling. Cell Host Microbe. 2012 FEB 16;11(2):153-66. Doi: 10.1016/j.chom.2012.01.008. PMID: 22341464
Tilstra JS, Robinson AR, Wang J, Gregg SQ, Clauson CL, Reay DP, Nasto LA, St Croix CM, Usas A, Vo N, Huard J, Clemens PR, Stolz DB, Guttridge DC, Watkins SC, Garinis GA, Wang Y, Niedernhofer LJ, Robbins PD. NF-ᴋB inhibition delays DNA damage-induced senescence and aging in mice. J Clin Invest. 2012 Jul 2;122(7):2601-12. Doi: 10.1172/JC145785. Epub 2012 Jun 18. PMID: 22706308
Gamper AM, Qiao X, Kim J, Zhang L, DeSimone MC, Rathmell WK, Wan Y. Regulation of KLF4 turnover reveals an unexpected tissue-specific role of pVHL in tumorigenesis. PMID:22284679[PubMed - indexed for MEDLINE] PMCID:PMC3982234Free PMC Article
Jha A, Watkins SC, Traub LM. The apoptotic engulfment protein Ced-6 participates in clathrin-mediated yolk uptake in Drosophila egg chambers. Mol Biol Cell. 2012 May;23(9):1742-64. doi: 10.1091/mbc.E11-11-0939. Epub 2012 Mar 7. PMID: 22398720
Boote C, Du Y, Morgan S, Harris J, Kamma-Lorger CS, Hayes S, Lathrop KL, Roh DS, Burrow MK, Hiller J, Terrill NJ, Funderburgh JL, Meek KM. Quantitative assessment of ultrastructure and light scatter in mouse corneal debridement wounds. Invest Ophthalmol Vis Sci. 2012 May 14;53(6):2786-95. doi: 10.1167/iovs.11-9305. PMID: 22467580
Du Y, Roh DS, Mann MM, Funderburgh ML, Funderburgh JL, Schuman JS. Multipotent stem cells from trabecular meshwork become phagocytic TM cells. Invest Ophthalmol Vis Sci. 2012 Mar 21;53(3):1566-75. doi: 10.1167/iovs.11-9134. PMID: 22297497
Stephenson-Famy A, Marks J, Suresh A, Caritis SN, Simhan H, Jeyasuria P, Condon JC. Antiapoptotic signaling via MCL1 confers resistance to caspase-3-mediated apoptotic cell death in the pregnant human uterine myocyte. Mol Endocrinol. 2012 Feb;26(2):320-30. doi: 10.1210/me.2011-1282. Epub 2011 Dec 22. PubMed PMID: 22194343; PubMed Central PMCID: PMC3275163.
Rbaibi Y, Cui S, Mo D, Carattino M, Rohatgi R, Satlin LM, Szalinski CM, Swanhart LM, Fölsch H, Hukriede NA, Weisz OA. OCRL1 modulates cilia length in renal epithelial cells. Traffic. 2012 Sep;13(9):1295-305. doi: 10.1111/j.1600-0854.2012.01387.x. Epub 2012 Jul 4. PMID: 22680056
Umasankar PK, Sanker S, Thieman JR, Chakraborty S, Wendland B, Tsang M, Traub LM. Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning. Nat Cell Biol. 2012 Apr 8;14(5):488-501. doi: 10.1038/ncb2473. PMID: 22484487
Gregg SQ, Gutiérrez V, Robinson AR, Woodell T, Nakao A, Ross MA, Michalopoulos GK, Rigatti L, Rothermel CE, Kamileri I, Garinis GA, Stolz DB, Niedernhofer LJ. A mouse model of accelerated liver aging caused by a defect in DNA repair. Hepatology. 2012 Feb;55(2):609-21. doi: 10.1002/hep.24713.PMID:21953681[PubMed - indexed for MEDLINE] Free PMC Article
Lapierre LA, Avant KM, Caldwell CM, Oztan A, Apodaca G, Knowles BC, Roland JT, Ducharme NA, Goldenring JR. Phosphorylation of Rab11-FIP2 regulates polarity in MDCK cells.Mol Biol Cell. 2012 Jun;23(12):2302-18. doi: 10.1091/mbc.E11-08-0681. Epub 2012 May 2.PMID:22553350[PubMed - indexed for MEDLINE] Free PMC Article
Colletti GA, Miedel MT, Quinn J, Andharia N, Weisz OA, Kiselyov K. Loss of lysosomal ion channel transient receptor potential channel mucolipin-1 (TRPML1) leads to cathepsin B-dependent apoptosis. J Biol Chem. 2012 Mar 9;287(11):8082-91. doi: 10.1074/jbc.M111.285536. Epub 2012 Jan 18.PMID:22262857[PubMed - indexed for MEDLINE] Free PMC Article
Fujita M, Mehra R, Lee SE, Roh DS, Long C, Funderburgh JL, Ayares DL, Cooper DK, Hara H. Comparison of proliferative capacity of genetically-engineered pig and human corneal endothelial cells. Ophthalmic Res. 2013;49(3):127-38. Doi: 10.1159/000342978. Epub 2012 Dec 18. PMID: 23258190
2011
Keyel PA, Loultcheva L, Roth R, Salter RD, Watkins SC, Yokoyama WM, Heuser JE. Streptolysin O clearance through sequestration into belbs that bud passively from the plasma membrane.J Cell Sci. 2011 Jul 15;124(Pt 14):2414-23. Doi: 10.1242/jcs.076182. Epub 2011 Jun 21. PMID: 21693578
Mukherjee A, Morosky SA, Delorme-Axford E, Dybdahl-Sissoko N, Oberste MS, Wang T, Coyne CB. The coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signaling. PLoS Pathog. 2011 Mar;7(3):e1001311. doi: 0.1371/journal.ppat.1001311. Epub 2011 Mar 10.PMID:21436888[PubMed - indexed for MEDLINE] Free PMC Article PMID: 21436888
Roh, DS, Funderburgh JL. Rapid changes in connexin-43 in response to genotoxic stress sstabilize cell-cell communication in corneal endothelium Invest Ophthalmol Vis Sci. 2011 Jul 15;52(8): 5174-82. Doi: 10.1167/iovs. 11-7272. PMID: 21666237
Bernal PJ, Bauer EM, Cao R, Maniar S, Mosher M, Chen J, Wang QJ, Glorioso JC, Pitt BR, Watkins SC, St Croix CM. A role for zinc in regulating hypoxia-induced contractile events in pulmonary endothelium. Am J Physiol Lung Cell Mol Physiol. 2011 Jun;300(6):L874-86. doi: 10.1152/ajplung.00328.2010. Epub 2011 Mar 4. PMID: 21378023
Delorme-Axford E, Coyne CB. The actin cytoskeleton as a barrier to virus infection of polarized epithelial cells. Viruses. 2011 Dec;3(12):2462-77. doi: 10.3390/v3122462. Epub 2011 Dec 21. PMID: 22355449
Mukherjee A, Morosky SA, Delorme-Axford E, Dybdahl-Sissoko N, Oberste MS, Wang T, Coyne CB. The coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signaling. PLoS Pathog. 2011 Mar;7(3):e1001311. doi: 10.1371/journal.ppat.1001311. Epub 2011 Mar 10. PMID: 21436888 [PubMed - indexed for MEDLINE] Free PMC Article
Choi S, Wang W, Ribeiro AJ, Kalinowski A, Gregg SQ, Opresko PL, Niedernhofer LJ, Rohde GK, Dahl KN. Computational image analysis of nuclear morphology associated with various nuclear-specific aging disorders. Nucleus. 2011 Nov-Dec;2(6):570-9. doi: 10.4161/nucl.2.6.17798. Epub 2011 Nov 1. PMID: 22127259
Wood MA, Mukherjee P, Toocheck CA, Walker WH. Upstream stimulatory factor induces Nr5a1 and Shbg gene expression during the onset of rat Sertoli cell differentiation. Biol Reprod. 2011 Nov;85(5):965-76. doi: 10.1095/biolreprod.111.093013. Epub 2011 Jul 6. PMID: 21734262
Butterworth MB, Edinger RS, Silvis MR, Gallo LI, Liang X, Apodaca G, Frizzell RA, Johnson JP. Rab11b regulates the trafficking and recycling of the epithelial sodium channel (ENaC. Am J Physiol Renal Physiol. 2012 Mar 1;302(5):F581-90. doi: 10. 1152/ ajprenal. 00304. 2011. Epub 2011 Nov 30. Erratum in: Am J Physiol Renal Physiol. 2012 Jul;303(1):F163. PMID: 22129970
Block ER, Tolino MA, Klarlund JK. Extracellular ATP stimulates epithelial cell motility through Pyk2-mediated activation of the EGF receptor. Cell Signal. 2011 Dec;23(12):2051-5. doi: 10.1016/j.cellsig.2011.07.021. Epub 2011 Aug 4. PMID: 21840393
Tolino MA, Block ER, Klarlund JK. Brief treatment with heparin-binding EGF-like growth factor, but not with EGF, is sufficient to accelerate epithelial wound healing. Biochim Biophys Acta. 2011 Sep;1810(9):875-8. doi: 10.1016/j.bbagen.2011.05.011. Epub 2011 May 26. PMID: 21640162
Klarlund JK, Block ER. Free edges in epithelia as cues for motility. Cell Adh Migr. 2011 Mar-Apr;5(2):106-10. Epub 2011 Mar 1. PMID: 20953155
Bhatia SR, Miedel MT, Chotoo CK, Graf NJ, Hood BL, Conrads TP, Silverman GA, Luke CJ. Using C. elegans to identify the protease targets of serpins in vivo. Methods Enzymol. 2011;499:283-99. PMID: 21683259
Gregg SQ, Gutiérrez V, Robinson AR, Woodell T, Nakao A, Ross MA, Michalopoulos GK, Rigatti L, Rothermel CE, Kamileri I, Garinis G, Stolz DB, Niedernhofer LJ. A mouse model of accelerated liver aging due to a defect in DNA repair. Hepatology. 2012 Feb;55(2):609-21. doi: 10.1002/hep.24713.PMID:21953681 Free PMC Article
Gregg SQ, Robinson AR, Niedernhofer LJ. Physiological consequences of defects in ERCC1-XPF DNA repair endonuclease. DNA Repair (Amst). 2011 Jul 15;10(7):781-91. Epub 2011 May 25. PMID: 2162988
Hu D, Qiao X, Wu G, Wan Y. The emerging role of APC/C(Cdh1) in development. Semin Cell Dev Biol. 2011 Aug;22(6):579-85. Epub 2011 Apr 7. PMID:21497201Free PMC Article
Jeyasuria P, Subedi K, Suresh A, Condon JC. Elevated levels of uterine anti-apoptotic signaling may activate NFKB and potentially confer resistance to caspase 3-mediated apoptotic cell death during pregnancy in mice. Biol Reprod. 2011 Aug;85(2):417-24. Epub 2011 May 12. PMID:21566000[PubMed - indexed for MEDLINE] Free PMC Article
Bhatia SR, Miedel MT, Chotoo CK, Graf NJ, Hood BL, Conrads TP, Silverman GA, Luke CJ. Using C. elegans to identify the protease targets of serpins in vivo. Methods Enzymol. 2011;499:283-99. doi: 10.1016/B978-0-12-386471-0.00014-6. PMID:21683259 [PubMed - indexed for MEDLINE]
Gregg SQ, Robinson AR, Niedernhofer LJ. Physiological consequences of defects in ERCC1-XPF DNA repair endonuclease. DNA Repair (Amst). 2011 Jul 15;10(7):781-91. doi: 10.1016/j.dnarep.2011.04.026. Epub 2011 May 25. Review.PMID:21612988[PubMed - indexed for MEDLINE] Free PMC Article Teisanu RM, Chen H, Matsumoto K, McQualter JL, Potts E, Foster WM, Bertoncello I, Stripp BR. Functional Analysis of Two Distinct Bronchiolar Progenitors during Lung Injury and Repair. Am J Respir Cell Mol Biol. 2011 Jun;44(6):794-803. Doi: 10.1165/rcmb.2010-0098OC. Epub 2010 Jul 23. PMID: 20656948
2010
Du Y, Roh DS, Funderburgh ML, Mann MM, Marra KG, Rubin JP, Li X, Funderburgh JL. Adipose-derived stem cells differentiate to keratocytes in vitro. Mol Vis. 2010 Dec 10;16:268009. PMID: 21179234
Bailey MA, Grabe M, Devor DC. Characterization of the PCMBS-dependent modification of KCa3.1 channel gating. J Gen Physiol. 2010 Oct;136(4):367-87. doi: 10.1085/jgp.201010430. Epub 2010 Sep 13. PMID: 20837673
Gao Y, Balut CM, Bailey MA, Patino-Lopez G, Shaw S, Devor DC. Recycling of the Ca2+activated K+ channel, KCa2.3, is dependent upon RME-1, Rab35/EP164C, and an N-terminal domain. J Biol Chem. 2010 Jun 4;285(23):17938-53. doi: 10.1074/jbc.M109.086553. Epub 2010 Apr 1. PMID: 20360009
Block ER, Tolino MA, Lozano JS, Lathrop KL, Sullenberger RS, Mazie AR, Klarlund JK. Free edges in epithelial cell sheets stimulate epidermal growth factor receptor signaling. Mol Biol Cell. 2010 Jul 1;21(13):2172-81. doi: 10.1091/mbc.E09-12-1026. Epub 2010 May 12. PMID: 20462956
Block ER, Tolino MA, Klarlund JK. Pyk2 activation triggers epidermal growth factor receptor signaling and cell motility after wounding sheets of epithelial cells. J Biol Chem. 2010 Apr 30;285(18):13372-9. doi: 10.1074/jbc.M109.083089. Epub 2010 Mar 9. PMID: 20215112
Constantinescu D, Csoka AB, Navara CS, Schatten GP. Defective DSB repair correlates with abnormal nuclear morphology and is improved with FTI treatment in Hutchinson-Gilford progeria syndrome fibroblasts. Exp Cell Res. 2010 Oct 15;316(17):2747-59. doi: 10.1016/j.yexcr.2010.05.015. Epub 2010 Jun 25.PMID: 20599958[PubMed - indexed for MEDLINE]
Teisanu RM, Chen H, Matsumoto K, McQualter JL, Potts E, Foster WM, Bertoncello I, Stripp BR. Functional analysis of two distinct bronchiolar progenitors during lung injury and repair. Am J Respir Cell Mol Biol. 2011 Jun;44(6):794-803. doi: 10.1165/rcmb.2010-0098OC. Epub 2010 Jul 23. PMID: 20656948
Bailey, M.A. , M. Grabe and D.C. Devor. Characterization of the PCMBS-dependent modification of KCa3.1 channel gating. J Gen Physiol. 2010 Oct;136(4):367-87. doi: 10.1085/jgp.201010430. Epub 2010 Sep 3.PMID:20837673Free PMC Article
Cui, S. , C.J. Guerriero, C.M. Szalinski, C.L. Kinlough, R.P. Hughey and O.A. Weisz. OCRL1 function in renal epithelial membrane traffic. Am. J. Physiol.: Renal Physiol. 298(2): F335-F345, 2010 PMID: 19940034
Gassei K, Ehmcke J, Wood MA, Walker WH, Schlatt S. Immature rat seminiferous tubules reconstructed in vitro express markers of Sertoli cell maturation after xenografting into nude mouse hosts. Mol Hum Reprod. 2010 Feb;16(2):97-110. doi: 10.1093/molehr/gap081. Epub 2009 Sep 21.PMID:19770206[PubMed - indexed for MEDLINE] Free PMC Article
Cui S,Guerriero CJ, Szalinski CM, Kinlough CL, Hughey RP, Weisz OA OCRL1 function in renal epithelial membrane traffic. Am J Physiol Renal Physiol. 2010 Feb;298(2):F335-45. doi: 10.1152/ajprenal.00453.2009. Epub 2009 Nov 25.PMID:19940034[PubMed - indexed for MEDLINE] Free PMC Article
Qiao X, Zhang L, Gamper AM, Fujita T, Wan Y. APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity. PMID:20935501[PubMed - indexed for MEDLINE] PMCID:PMC3047751Free PMC Article
Yang X, Wan Y, Qiao X, Arlet V, Li X. Transcriptional alteration of matrix-related gene expression in cultured human disc cells by nanoparticles of a bismethanophosphonate fullerene. PMID:20441571[PubMed - indexed for MEDLINE]
2009
Zemke AC, Teisanu RM, Giangreco A, Drake JA, Brockway BL, Reynolds SD, Stripp BR. Beta-Catenin is not necessary for maintenance or repair of the bronchiolar epithelium. Am J Respir Cell Mol Biol. 2009 Nov;41(5):535-43. doi: 10.1165/rcmb.2008-0407OC. Epub 2009 Feb 12. PMID: 19213872
Teisanu RM, Lagasse E, Whitesides JF, Stripp BR. Prospective isolation of bronchiolar stem cells based upon immunophenotypic and autofluorescence characteristics. Stem Cells. 2009 Mar;27(3):612-22. doi: 10.1634/stemcells.2008-0838. PMID: 19056905
Wood, M.A. and W.H. Walker W.H. USF1/2 Transcription Factor DNA-binding Activity is Induced During Sertoli Cell Differentiation. Biology of Reproduction. 80: 24-29, 2009. PMID: 18768914
Viswanathan, P., M.A. Wood and W.H. Walker. FSH Transiently Blocks FSH Receptor Transcription by Increasing ID2 and Decreasing Upstream Stimulatory Factor (USF) Expression in Rat Sertoli Cells. Endocrinology. 150: 3783-3791, 2009. PMID: 19423764
Roh, D.S. and J.L. Funderburgh. The Impact of Mitomycin-C During Photorefractive Keratectomy on the Corneal Endothelium. Journal of Refractive surgery. J. Refract. Surg. Oct;25(10):894-7, 2009. PMID:19835330Free PMC Article
Silvis, M.R. , C.A. Bertrand, N. Ameen, F. Golin-Bisello, M.B. Butterworth, R.A. Frizzell, N.A. Bradbury. Rab11b Regulates the Apical Recycling of CFTR in Polarized Intestinal Epithelial Cells. Mol Biol Cell. 20(8):2377-50, 2009. PMID: 19244346
Thieman, J.R. , S.K. Mishra, K. Ling, B. Doray, R.A. Anderson and L.M. Traub. Clathrin regulates the association of PIPKIgamma661 with the AP-2 adaptor beta2 appendage. J. Biol. Chem. 284(20): 13924-13939, 2009. PMID:19287005Free PMC Article
Silvis MR, Bertrand CA, Ameen N, Golin-Bisello F, Butterworth MB, Frizzell RA, Bradbury NARab11b regulates the apical recycling of the cystic fibrosis transmembrane conductance regulator in polarized intestinal epithelial cells. Mol Biol Cell. 2009 Apr;20(8):2337-50. doi: 0.1091/mbc.E08-01-0084. Epub 2009 Feb 25.PMID:19244346[PubMed - indexed
Snyder JC, Teisanu RM, Stripp BR. Endogenous lung stem cells and contribution to disease. J Pathol. 2009 Jan;217(2):254-64. doi: 10.1002/path.2473. Review. PMID:19039828[PubMed - indexed for MEDLINE] Free PMC Article
Giangreco A, Arwert EN, Rosewell IR, Snyder J, Watt FM, Stripp BR Stem cells are dispensable for lung homeostasis but restore airways after injury. Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9286-91. doi: 10.1073/pnas.0900668106. Epub 2009 May 28.PMID:19478060[PubMed - indexed for MEDLINE] Free PMC Article
Zemke AC, Teisanu RM Giangreco A, Drake JA, Brockway BL, Reynolds SD, Stripp BR. beta-Catenin is not necessary for maintenance or repair of the bronchiolar epithelium. Am J Respir Cell Mol Biol. 2009 Nov;41(5):535-43. doi: 10.1165/rcmb.2008-0407OC. Epub 2009 Feb 12.PMID:19213872[PubMed - indexed for MEDLINE] Free PMC Article
Snyder JC, Zemke AC, Stripp BR. Reparative capacity of airway epithelium impacts deposition and remodeling of extracellular matrix. Am J Respir Cell Mol Biol. 2009 Jun;40(6):633-42. Doi: 10.1165/rcmb.2008-0334OC. Epub 2008 Oct 31. PMID: 18978301 [PubMed – indexed for MEDLINE] Free PMC Article
Zemke AC, Snyder JC, Brockway BL, Drake JA, Reynolds SD, Kaminski N. Stripp BR. Molecular staging of epithelial maturation using secretory cell-specific genes as markers. Am J Respir Cell Mol Biol. 2009 Mar; 40 (3):340-8. Doi: 10.1165/rcmb. 2007-030OC. Epub 2008 Aug 28. PMID: 18757308 [PubMed – indexed for MEDLINE] Free PMC Article
Heitzer MD, Wolf IM, Sanchez ER, Witchel SF, DeFranco DB. Glucocorticoid receptor physiology. Rev Endocr metab Disord. 2007 Dec;8(4):321-30. Review. PMID:18059904 {PubMed – Indexed for MEDLINE}
2008
Block ER, Klarlund JK. Wounding sheets of epithelial cells activates the epidermal growth factor receptor through distinct short-and long-range mechanisms. Mol Biol Cell. 2008 Nov;19(11):4909-17. doi: 10.1091/mbc.E08-01-0097. Epub 2008 Sep 17. PMID: 18799627
Reynolds SD, Zemke AC, Giangreco A, Brockway BL, Teisanu RM, Drake JA, Mariani T, Di PY, Taketo MM, Stripp BR. Conditional stabilization of the beta-catenin expands the pool of lung stem cells. Stem Cells. 2008 May;26(5):1337-46. doi: 10.1634/stemcells.2008-0053. Epub 2008 Mar 20. PMID: 18356571
Miedel, M.T. , Y. Rbaibi, C.J. Guerriero, G. Colletti, K.M. Weixel, O.A. Weisz and K. Kiselyov. Membrane traffic and turnover in TRP-ML1 deficient cells: A revised model for Mucolipidosis Type IV pathogenesis. Journal of Experimental Medicine. 205:1477-1490, 2008. PMID:18504305
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Gao, Y., C.K. Chotoo, C.M. Balut, F. Sun, M.A. Bailey and D.C. Devor. Role of S3 and S4 transmembrane domain charged amino acids in channel biogenesis and gating of KCa2.3 and KCa3.1. J. Biol. Chem. 283(14): 9049-9059, 2008. Apr 14):9049-59. doi: 10.1074/jbc.M708022200. Epub 2008 Jan 8.PMID:18227067[PubMed - indexed for MEDLINE] Free PMC Article
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Bernal, P.J. , K. Leelavanichkul, E. Bauer, R. Cao, A. Wilson, K.J. Wasserloos, S.C. Watkins, B.R. Pitt and C.M. St Croix. Nitric-oxide-mediated zinc release contributes to hypoxic regulation of pulmonary vascular tone. Circ. Res. 102(12): 1575-1583, 2008. PMed: 18483408.
Mishra, S.K., A. Jha, A.L. Steinhauser, V.A. Kokoza, C.H. Washabaugh, A.S. Raikhel, W.A. Foster and L.M. Traub. Internalization of LDL receptor-superfamily yolk protein receptors during mosquito oogenesis involves transcriptional regulation of PTB domain adaptors. J Cell Sci. 2008 Apr 15;121(pt 8): 1264-74 Dpo" 10.1242/jcs.025833. PMID: 18388314 [PubMed – indexed for MEDLINE] Free Article
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