Cell Biology and Molecular Physiology

CBMP Faculty (click for complete list) have a common interest in understanding the cellular basis of life and disease. As most human diseases arise from failures on a cellular level, our faculty investigate the cellular underpinnings of kidney, heart, lung and brain diseases, cancer, diabetes and inherited diseases of development and reproduction. Their research can be divided into the following broad categories:

Membrane Traffic of Protein and Lipids

Many of our faculty study how cells assemble the molecular machinery to coordinate membrane and organelle transport. Studies investigate how errors in cellular trafficking result in disease. | Top
Representative Faculty: Apodaca, Aridor, Brodsky, Butterworth, Cunningham, Goetzman, Hammond, Hong, Hughey, Liu, Murray, Sekine, Sekine, Sorkin, Sun, Tan, Weisz

Cell Communication, Signaling and Ion Channel Biology

Studies aim to understand how cells receive, decode and transmit signals to establish complex signaling networks in the body. A breakdown in cellular communication leads to diseases like diabetes, neurodegenerative disease, cystic fibrosis, hypertension, heart disease and others, all under investigation by faculty. | Top
Representative Faculty: Brodsky, Butterworth, Carattino, Cunningham, Devor, Du, Dutta, Hammond, Hughey, Kashlan, Kleyman, Kwiatkowski, Lamitina, Liu, Murray, Roy, Salama, Saloman, Sekine, Sekine, Sims-Lucas, St. Croix, Stolz, Subramanya, Sun, Tan, Tsang, Vasudevan, Watkins, Watson, Weisz, Xing, Zhu

Cellular Injury, Wound Healing, Aging and Tissue Regeneration

Researchers are investigating responses to stress, cell or tissue damage to understand the cellular mechanisms that mediate repair and maintenance. This includes acute injury, chronic aging and new tissue growth. | Top
Representative Faculty: Cunningham, Du, Dutta, Ghazi, Kwiatkowski, Lamitina, Murray, Saloman, Sekine, Stolz, Swamynathan, Vasudevan, Xing, Yanowitz, Zhu

DNA Damage/Repair, Cell-Cycle Control and Gene Expression, Cancer

An undamaged genome is essential to prevent cancer. Our faculty strive to identify defects associated with the cellular response to DNA damage/repair and cancer. | Top
Representative Faculty: Ghazi, Leuba, Swamynathan, Walker, Weisz, Yanowitz

Genomics, Proteomics and Metabolomics

Faculty that aim to describe cellular function as a product of their genomic, proteomic or small molecule interactomes. | Top
Representative Faculty: Brodsky, Butterworth, Devor, Drain, Goetzman, Hong, Kwiatkowski, Lamitina, Liu, Sekine, Sims-Lucas, Sorkin, Weisz, Xing, Zhu

Reproductive Biology

Faculty specialize in the unique cellular processes associated with reproduction, and defects linked to reproductive disease and disorder. | Top
Representative Faculty: Ghazi, Schatten, Walker, Yanowitz

Complete CBMP Faculty List

A full list of CBMP Faculty and their research interests can be found here